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Finding Hope in Tragedy

After her daughter was born, Nancy [Guthrie] knew something was wrong. Though she named the baby Hope, there wasn't much to be hopeful about. Born with clubfeet, extreme lethargy, and an inability to suck, among other problems, Hope was officially diagnosed with Zeilweger Syndrome. This rare metabolic disorder is characterized by an absence of peroxisomes (cell structures that rid the body of toxic substances). There is no treatment or cure. Most babies with the disease live less than six months.

"At first, I thought it was my fault," says Nancy "that I didn't pray enough for a healthy baby and was now paying for it." Nancy was familiar with prayer. She grew up going to church, attended a Christian college, and had a great job in Christian publishing. Her life was filled with the pursuit of Christian ...

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